The Madonna and Child with Angels is a painting by the Italian Renaissance painter Masaccio, who worked in collaboration with his brother Giovanni and with Andrea di Giusto. The painting is the central panel of the Pisa Altarpiece, a large multi-paneled altarpiece executed for the chapel of St. Julian, owned by the notary Giuliano di Colino in the church of Santa Maria del Carmine in Pisa. The painting is in a very damaged state, the altarpiece having been cut up and sold in pieces long ago. Today the panel is smaller than its original state; it has lost perhaps as much as 8 cm. at the bottom and 2-2.5 cm. at each side.Eleven surviving panels of the altarpiece, which is the only documented work by Masaccio, are in various museums. Scholars hypothesize the reconstruction of the altarpiece based on a very complete description by Vasari.